All the directions are auspicious as per vastu and at the same time, each direction will have certain principle to follow, while constructing a house.
For south facing house also, if entrance is towards SE direction, it's considered to be good. Which side you have your south facing home entrance?
If you divide your south wall in nine equal portion from SE to SW, 4th portion from SE is the best for south facing home. 1st to 3rd are also ok. 5th till 9th, we should avoid as an entrance for south facing home.